Neury Thursday: Sleep and the Blood Brain Barrier, with some hesitation

The blood brain barrier (aka, BBB) can be a royal pain in the arse for pharmacologists and pharmaceutical companies. The ultimate goal of the neuro division of big pharm is to design drugs that can be taken orally and yet still cross the BBB with little issues. Billions of dollars can be gained or lost […]

Vampire Diaries: Tales of Sleep

Blood is making a comeback in neuroscience and psychology research. Centuries ago, Galen thought that personality and behavior were governed by the four “humors” with blood being one of them. A few months ago, blood gained some credibility in neuroscience when a study published in Nature found that the donation of blood collected from a […]

Sleep Position Matters.

Today, I got a deep tissue massage in an attempt to accelerate recovery from the Pensacola Beach Brawl. It is no surprise that I favor my right side; it is my dominant side. Even so, my massage therapist provided some insight that is so obvious yet so neglected and likely explains my long-term aches and […]

History of Sleep by the Father of Sleep, Himself

Last week, my undergraduate advisor, Dr. Mary Carskadon, who could arguably be called the “mother of sleep” given her long-standing contributions as a female scientist, sent me the following article. The article is about the life’s work of William C. Dement who many regard as the “father of sleep medicine.” I won’t spoil the contents […]

For Sleep but Sleepless in Lake Arrowhead, California

For the past week, I have been residing in high altitude at the UCLA-owned resort of Lake Arrowhead, California in the San Bernardino Forest (and mountains) near LA. I was attending a scientific and professional development workshop devoted to sleep research, grantsmanship, responsible conduct of research, and networking. The theme of the workshop was “translational […]

A non-invasive system to replace EEG/EMG recording of sleep

This week, we resumed our biweekly journal club in sleep and circadian rhythms for the year. I presented a paper published last week in the journal Sleep. It was more of a methods papers, but still important because non-invasive tools for measuring sleep have become best-sellers: FitBit, Zeo, and other Nike/iPod-based physical activity software. This […]

It’s Crossfit Games Week: #Pandanation, #AllBridgers, and #Jetlag

Years worth of training, competition, and trust come to fruition this weekend as my teammate, training partner, and friend competes for the title “Fittest on Earth.”  I’ve talked about the Crossfit Games and the journey that it takes to get there many times before. Last year, I had the opportunity to compete on a team […]

Characterizing Sleep-Wake States in a Cat

For those of you not schooled in the history of sleep, the use of a cat as an animal model of sleep may seem novel. However, the cat was used as an animal model of sleep decades before rats, mice, hamsters, monkeys, and other non-human mammals. In fact, one of the first studies to identify […]

Daylight Savings is a Public Health Concern. Who is responsible? The circadian system or sleep homeostat?

This isn’t new news. For years, public health officials have forewarned us about the increased risks for car accidents, workplace accidents, and immediate declines in cardiovascular and neurological health following the springing forward. Nearly all of these studies attribute the connection between DST and changes in health risks to an hour of sleep loss because […]

Highlights from the Gordon Conference on Sleep Regulation

I have been idle the past week because I have been in Galveston, TX for a secret society meeting of sleep researchers. It wasn’t really secret, but it was an invite only conference limited to less than 200 participants worldwide. The focus of the meeting was the neural mechanisms of sleep, namely those studied in […]

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