Comments for Dormivigilia

Comment on My Doctoral Diploma: Per2, Circadian Rhythms, and Coke by Allison

Allison — Sat, 27 Apr 2013 23:37:08 +0000

Actually, it wasn’t that bad probably because humans can’t metabolize the cocaine given to rodents very well (cocaine hydrochloride) and vice versa; Plus, we already had a fairly sensitive microbalance. The only conundrum was that there was only one person in the entire dept who was allowed to dispense the cocaine (and it wasn’t my PI) so it sucked whenever she was on vacation. Otherwise, we just had to be mindful of random drug testing, which never happened, but I’m pretty sure that they would have only tested for cocaine and not another illicit drug that is nearly legal at this point anyways….or so we kept telling ourselves.

Comment on My Doctoral Diploma: Per2, Circadian Rhythms, and Coke by Nat

Nat — Fri, 26 Apr 2013 03:33:23 +0000

Blog idea: The hurdles you have to get over to actually use cocaine in research. Ethics, where do you order it from, how do you have to store it, security etc

Comment on Bmal1 Regulation of Metabolism, Cont’d by Allison

Allison — Wed, 13 Mar 2013 02:42:33 +0000

somehow that did not pop up in my weekly pubmed notification. thanks! This is perfect timing because we just submitted a paper to PLoS looking at the interactions between insufficient sleep, jet lag, and inflammatory responses (in mice, of course). And as far as Daylight Savings, there are only two states unfortunately who see the idiocracy of it …I’m not sure how that works out in the business world though…..

Comment on Bmal1 Regulation of Metabolism, Cont’d by Nat

Nat — Sun, 10 Mar 2013 23:45:43 +0000

What did you think about the one in PNAS the other week? (Moller-Levet)

Comment on Sleep Awareness Week by Nat

Nat — Sun, 10 Mar 2013 23:09:20 +0000

It doesn’t matter whether it’s the sleep deprivation or the circadian dislocation or both causing the problem. The public policy implication is clear: stop having daylight savings. It doesn’t save power and it might be causing harm and so the precautionary principal applies.

I still haven’t heard any really good argument for keeping it.

Comment on Consequences of Night Shift Work by Nat

Nat — Tue, 29 Jan 2013 23:28:59 +0000

We’ve been employed under the same training grant in sleep http://www.cirus.org.au

The physics arm of our grant makes us feel like idiots too…

Comment on Consequences of Night Shift Work by Allison

Allison — Mon, 14 Jan 2013 22:14:11 +0000

I presume you know her? I've been real impressed with her work. She had a paper similar to this one in JBR in early 2012. I definitely feel like an idiot reading these papers because of my lack of knowledge of computational biology. This is some really complex stuff. However, it's nice to see this conducted in human shift workers. It definitely lends some translational significance to a study that we are hoping to publish soon. We got animals on a long schedule of weekly shift work and are looking at daily changes in sleep-wake as well as some immune responses.

Comment on Consequences of Night Shift Work by Nat

Nat — Mon, 14 Jan 2013 21:51:25 +0000

Nice one Svetlana

Comment on Introducing Cryotherapy by Allison

Allison — Thu, 13 Dec 2012 04:48:08 +0000

Yes, I’m in the process of testing that hypothesis…it’s a repeated measures design with an n of 6 (myself and my teammates). But there’s no denying how cold you get during that three minutes; you shiver pretty quickly and it feels great (honestly).

Comment on Introducing Cryotherapy by Nat

Nat — Thu, 13 Dec 2012 00:44:30 +0000

I bet it’s got one hell of a placebo response too