What Kind Of Brain Does It Take to Do This?

Mike Wilson does a quadruple back flip into Lake Tahoe from a 99 foot rope swing  suspended from a mountain. Can you imagine the serious amounts of endorphins being released from his body before and during this stunt??? Because obviously, you can’t frack up……

Muscle Health Is Circadian-Dependent

I apologize for the meager amount of posts this past week, but a looming deadline of an NIH grant and paper submission have consumed my life. But in between drinking cups of americano at Starbucks, I did happen to read a really cool, game-changing (er, field-changing) paper in PNAS. A team of circadian researchers, including […]

Scientific Lunancy: Light Treatment for SAD

It’s well known that blue light therapy is an effective treatment for seasonal affective disorder. It’s only efficacious, however, when the patient stares at the blue light straight-on, not just simply be in an ambient room, like a swanky martini bar, with blue light. And it’s especially not efficacious if the blue light emission is […]

Goodbye SfN San Deigo

No more beaches, no more palm trees, and no more deliciously spicy Mexicana salsa. Hello cold, hello snow, and hello bare ugly brown trees. But at least I am returning with some new swag and have become a member of AAAS (even if my motivation for doing so was driven by a free T-shift about […]

Posters In Brief

Cao et al: MSK KO mice (a critical molecular component of the photic signaling cascade) show attenuated photic entrainment Agha et al: BDNF shows circadian expression Han et al: Sodium channel loss causes epilepsy in mice and impairs circadian behavioral and genetic responses to light. Excalibur et al: PER and CLOCK expression in crayfish peak […]

Posters In Brief

Here are a few highlights from today’s poster sessions: Hagenbauer et al: Differences in Per gene expression exist in mid and post-pubertal degus, a diurnal rodent Evans et al: Exposure to longer photoperiods causes a reorganization of the neuron populations in the SCN. Also, exercise can restore circadian entrainment in VIP Knockout mice And there […]

Sleep Restriction, Pain Sensitivity, and Anxiety

This morning, I went to Balboa Park to see the botanical gardens. But this afternoon, I went to a 2.5 hr symposium devoted to the deleterious effects of sleep deprivation on physiology. There is unanimous evidence that sleep restriction enhances pain sensitivity even in the presence of an analgesic like morphine. Also, during the symposium […]

Elucidating the molecular circadian clock

Today there were two symposia devoted to better understandimg the powers of the circadian molecular machinery. The first talk given by Joe Takahashi from the Howard Hughes Institute focused on body temperature rhythms and reaching an understanding as to why the master SCN clock does not molecularly or physiologically respond to abrupt temperature changes whereas […]

Posters In Brief

Today, I presented so I didn’t have much of an opportunity to cruise around the gazillion posters. But of the few I did see: 1. Fagerberg et al: Glycine modulates EtOH intake. Enhancing glycine activity decreases drinking and vice versa and most likely, acamprosate (a drug alcoholics take to reduce relapse) acts through glycine to […]

Why Glenn Close’s Lecture Is Perfect Timing

For those of you neurobloggers who may also be members of the skeptics/scientific inquiry community may know, Glenn Close’s appearance at this year’s Society for Neuroscience opening keynote address is very fortunate. Over the past year, there have been numerous news reports about the pseudoscientific finding’s of Andrew Wakefield which show an “alleged” link between […]

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