Cao et al: MSK KO mice (a critical molecular component of the photic signaling cascade) show attenuated photic entrainment
Agha et al: BDNF shows circadian expression
Han et al: Sodium channel loss causes epilepsy in mice and impairs circadian
behavioral and genetic responses to light.
Excalibur et al: PER and CLOCK expression in crayfish peak midday and at lights off, respectively, which is comparable to the rhythms in mammals.
Karmarkar et al : glutamate mediates cell survival and death
Irwin et al: VIP decreases neuron firing whereas AVP increases it
Westrich et al: lithium lengthens the free running period of behavioral rhythms
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2 Comments until now
Interesting about crayfish…. I am assuming none of this is published yet?
I’m not certain whether Jenn Evans used mouse or rat, but I’m assuming mouse since their lab uses them for other experiments. It was definitely in vitro. They have this cool 3D microscope that can assess the phase of many regions of the SCN and determine which regions “lag” behind others, or advance.
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